Blar i Bergen Open Research Archive på forfatter "Henne, Nina"
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Influence of chain length on the activity of tripeptidomimetic antagonists for CXC chemokine receptor 4 (CXCR4)
Baumann, Markus; Hussain, Mohammad Musarraf; Henne, Nina; Garrote, Daniel Moya; Karlshøj, Stefanie; Fossen, Torgils; Rosenkilde, Mette M.; Våbenø, Jon; Haug, Bengt Erik (Peer reviewed; Journal article, 2017-01)Here we report a series of close analogues of our recently published scaffold-based tripeptidomimetic CXCR4 antagonists, containing positively charged guanidino groups in R1 and R2, and an aromatic group in R3. While ... -
Serum concentrations of active tamoxifen metabolites predict long-term survival in adjuvantly treated breast cancer patients
Helland, Thomas; Henne, Nina; Bifulco, Ersilia; Naume, Bjørn; Borgen, Elin; Kristensen, Vessela N.; Kvaløy, Jan Terje; Lash, Timothy L; Grenaker, Grethe Irene; van Schaik, RHN; Janssen, Emiel; Hustad, Simon Steinar; Lien, Ernst Asbjørn; Mellgren, Gunnar; Søiland, Håvard (Peer reviewed; Journal article, 2017-11-28)Background: Controversies exist as to whether the genetic polymorphisms of the enzymes responsible for the metabolism of tamoxifen can predict breast cancer outcome in patients using adjuvant tamoxifen. Direct measurement ...